| 產(chǎn)品編號(hào) | bsm-63305R |
| 英文名稱 | phospho-HER2 (Y1139) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化HER2受體重組兔單抗 |
| 別 名 | CD340; CerbB2; ERBB2; HER2; Herstatin; MLN19; NEU; NGL; p185erbB2; TKR1. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 1H2 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 138 kDa |
| 檢測(cè)分子量 | 180 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human ErbB2 around the phosphorylation site of Y1139: PE-pY-VN |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. SWISS: P04626 Gene ID: 2064 細(xì)胞膜受體（Membrane Receptors) c-erbB-2癌基因，在很多癌組織中呈C-erbB-2過(guò)度表達(dá)。cerbB尤其臨床常用于乳腺癌術(shù)后C-erbB-2蛋白、雌激素受體（ER）和孕激素受體（PR）表達(dá)情況，旨在進(jìn)一步探討癌基因蛋白，細(xì)胞增殖活性和激素受體與乳腺癌組織學(xué)分級(jí)及術(shù)后生存期的關(guān)系，為乳腺癌的病理診斷、預(yù)后判斷及治療提供依據(jù)。 |
