產(chǎn)品編號(hào) | bs-41598P |
英文名稱(chēng) | Recombinant Human BMP4 Protein (E399D), No Tag |
中文名稱(chēng) | 重組人骨形態(tài)發(fā)生蛋白4 |
別 名 | BMP 4; BMP2B; BMP2B1; Bone morphogenetic protein 4; DVR4; ZYME; BMP4_HUMAN; BMP-4; Bone morphogenetic protein 2B; BMP-2B. |
理論分子量 | 13.25kDa |
性 狀 | Liquid |
濃 度 | >0.5mg/ml |
純 度 | ≥ 95 % as determined by SDS-PAGE. |
緩 沖 液 | Lyophilized from sterile 30% Acetonitrile, 1/1000 TFA. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix. SWISS: P12644 Gene ID: 652 骨形態(tài)發(fā)生蛋白-4(BMP4)是轉(zhuǎn)化生長(zhǎng)因子β超家族成員,也參與器官發(fā)生,細(xì)胞增殖、分化及凋亡等。 |