| 產(chǎn)品編號(hào) | bs-0361P-HRP |
| 英文名稱 | Recombinant protein G |
| 中文名稱 | HRP標(biāo)記的重組蛋白G |
| 別 名 | reProtein G; Protein G recombinant; Immunoglobulin G-binding protein G; IgG-binding protein G; SPG1_STRSG |
| 檢測(cè)分子量 | 22 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 純 度 | >90% as determined by SDS-PAGE |
| 緩 沖 液 | Lyophilized powder. |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Protein G is an immunoglobulin-binding protein expressed in group C and G Streptococcal bacteria much like Protein A but with differing specificities. It is a 65-kDa (G148 protein G) and a 58 kDa (C40 protein G)[1] cell surface protein that has found application in purifying antibodies through its binding to the Fc region. The native molecule also binds albumin, however, because serum albumin is a major contaminant of antibody sources, the albumin binding site has been removed from recombinant forms of Protein G. Recombinant protein G has a very high affinity for the Fc regions of IgG molecules. Immoblisation of protein G on beads creates an affinity resin which can be used to purify IgG fractions from crude serum, ascites fluid or cell cuture media. Recomb Protein G 蛋白G是從G類Streptococci細(xì)菌中分離出來的胞壁蛋白，與多數(shù)哺乳動(dòng)物的IgG Fc段結(jié)合（包括：人、山羊、綿羊、兔、豚鼠、馬、豬、猴、小鼠等），分子量：22kDa。不與狗IgG結(jié)合、不結(jié)合人IgM、IgD、和IgA。 重組蛋白G（Recomb Protein G）已經(jīng)除去了與白蛋白及細(xì)胞表面結(jié)合位點(diǎn)，減少了交叉反應(yīng)和非特異性結(jié)合。因此，它比天然蛋白G和蛋白A有更大的親和力?？梢源娑? |
