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RASD2 Rabbit pAb (bs-7006R)  
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產(chǎn)品編號 bs-7006R
英文名稱 RASD2 Rabbit pAb
中文名稱 腫瘤血管內(nèi)皮標記蛋白2抗體
別    名 GTP binding protein Rhes; GTP-binding protein Rhes; Ras homolog enriched in striatum; RASD 2; RASD family member 2; RASD2; Rhes; RHES_HUMAN; TEM 2; TEM2; Tumor endothelial marker 2.  
研究領域 腫瘤  信號轉導  生長因子和激素  細胞類型標志物  腫瘤細胞生物標志物  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 30 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASD2: 201-266/266 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.

Function:
GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.

Subunit:
Monomer (Potential). Interacts with PIK3CA and UBE2I. Interacts with GNB1, GNB2 and GNB3. Interacts with HTT; interacts with mutant HTT (mHTT) with a much higher affinity than wild type HTT.

Subcellular Location:
Cell membrane; Lipid-anchor.

Tissue Specificity:
Pancreatic endocrine cells (islets of Langerhans).

Post-translational modifications:
Farnesylated. Farnesylation is required for membrane targeting.

Similarity:
Belongs to the small GTPase superfamily. RasD family.

SWISS:
Q96D21

Gene ID:
23551

Database links:

Entrez Gene: 23551 Human

Entrez Gene: 75141 Mouse

Entrez Gene: 171099 Rat

Omim: 612842 Human

SwissProt: Q96D21 Human

SwissProt: P63032 Mouse

SwissProt: P63033 Rat

Unigene: 474711 Human

Unigene: 179267 Mouse

Unigene: 115571 Rat



產(chǎn)品圖片
Sample: U87MG(Human) Cell Lysate at 30 ug Primary: Anti- RASD2 (bs-7006R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD
Sample: A549(Human) Cell Lysate at 30 ug Siha(Human) Cell Lysate at 30 ug Primary: Anti- RASD2 (bs-7006R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD
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